PDBe 1d2s

X-ray diffraction
1.55Å resolution

CRYSTAL STRUCTURE OF THE N-TERMINAL LAMININ G-LIKE DOMAIN OF SHBG IN COMPLEX WITH DIHYDROTESTOSTERONE

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Sex hormone-binding globulin Chain: A
Molecule details ›
Chain: A
Length: 170 amino acids
Theoretical weight: 18.86 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P04278 (Residues: 42-217; Coverage: 46%)
Gene name: SHBG
Sequence domains: Laminin G domain
Structure domains: Jelly Rolls

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X11
Spacegroup: R32
Unit cell:
a: 104.04Å b: 104.04Å c: 84.43Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.21 0.205 0.251
Expression system: Escherichia coli