PDBe 1cx8

X-ray diffraction
3.2Å resolution

CRYSTAL STRUCTURE OF THE ECTODOMAIN OF HUMAN TRANSFERRIN RECEPTOR

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transferrin receptor protein 1, serum form Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 639 amino acids
Theoretical weight: 71.62 KDa
Source organism: Homo sapiens
Expression system: Cricetinae gen. sp.
UniProt:
  • Canonical: P02786 (Residues: 122-760; Coverage: 84%)
Gene name: TFRC
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F1
Spacegroup: P212121
Unit cell:
a: 105.4Å b: 216.9Å c: 361.9Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.243 0.243 0.284
Expression system: Cricetinae gen. sp.