PDBe 1cmo

Solution NMR

IMMUNOGLOBULIN MOTIF DNA-RECOGNITION AND HETERODIMERIZATION FOR THE PEBP2/CBF RUNT-DOMAIN

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Runt-related transcription factor 1 Chain: A
Molecule details ›
Chain: A
Length: 127 amino acids
Theoretical weight: 14.01 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q01196 (Residues: 52-178; Coverage: 28%)
  • Best match: Q01196-11 (Residues: 1-73)
Gene names: AML1, CBFA2, RUNX1
Structure domains: Immunoglobulin-like

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: HYBRID DISTANCE GEOMETRY/SIMULATED ANNEALING
Expression system: Escherichia coli BL21(DE3)