PDBe 1cfa

Solution NMR

SOLUTION STRUCTURE OF A SEMI-SYNTHETIC C5A RECEPTOR ANTAGONIST AT PH 5.2, 303K, NMR, 20 STRUCTURES

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
SYNTHETIC N-TERMINAL TAIL Chain: B
Molecule details ›
Chain: B
Length: 4 amino acids
Theoretical weight: 449 Da
Source organism: Unidentified
Expression system: Not provided
C5a anaphylatoxin Chain: A
Molecule details ›
Chain: A
Length: 71 amino acids
Theoretical weight: 7.95 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P01031 (Residues: 679-747; Coverage: 4%)
Gene names: C5, CPAMD4
Sequence domains: Anaphylotoxin-like domain
Structure domains: Anaphylotoxins (complement system)

Ligands and Environments

No bound ligands

1 modified residue:

Experiments and Validation Details

Entry percentile scores
Expression systems:
  • Not provided
  • Escherichia coli