PDBe 1c7d

X-ray diffraction
1.8Å resolution

DEOXY RHB1.2 (RECOMBINANT HEMOGLOBIN)

Released:
Source organism: Homo sapiens
Primary publication:
Genetically crosslinked hemoglobin: a structural study.
Acta Crystallogr. D Biol. Crystallogr. 56 812-6 (2000)
PMID: 10930828

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Hemoglobin subunit beta Chains: B, D
Molecule details ›
Chains: B, D
Length: 146 amino acids
Theoretical weight: 15.94 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P68871 (Residues: 2-147; Coverage: 99%)
Gene name: HBB
Sequence domains: Globin
Structure domains: Globins
Hemoglobin subunit alpha Chain: A
Molecule details ›
Chain: A
Length: 284 amino acids
Theoretical weight: 30.43 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P69905 (Residues: 2-142; Coverage: 99%)
Gene names: HBA1, HBA2
Sequence domains: Globin
Structure domains: Globins

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SIEMENS
Spacegroup: P21
Unit cell:
a: 63.144Å b: 83.282Å c: 53.928Å
α: 90° β: 99.07° γ: 90°
R-values:
R R work R free
0.189 not available 0.24
Expression system: Escherichia coli