PDBe 1bz8

X-ray diffraction
2Å resolution

TRANSTHYRETIN (DEL VAL122)

Released:
Source organism: Homo sapiens
Entry authors: Schormann N, Uemichi T, Benson MD

Function and Biology Details

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transthyretin Chains: A, B
Molecule details ›
Chains: A, B
Length: 126 amino acids
Theoretical weight: 13.68 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P02766 (Residues: 21-147; Coverage: 99%)
Gene names: PALB, TTR
Sequence domains: HIUase/Transthyretin family
Structure domains: Transthyretin/hydroxyisourate hydrolase domain

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P21212
Unit cell:
a: 43.33Å b: 86.75Å c: 65.05Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.193 0.193 0.277
Expression system: Escherichia coli