PDBe 1bp1

X-ray diffraction
2.4Å resolution

CRYSTAL STRUCTURE OF BPI, THE HUMAN BACTERICIDAL PERMEABILITY-INCREASING PROTEIN

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Bactericidal permeability-increasing protein Chain: A
Molecule details ›
Chain: A
Length: 456 amino acids
Theoretical weight: 50.7 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
  • Canonical: P17213 (Residues: 32-487; Coverage: 100%)
Gene name: BPI
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH2R
Spacegroup: C2
Unit cell:
a: 185.6Å b: 33Å c: 85.2Å
α: 90° β: 101.6° γ: 90°
R-values:
R R work R free
0.225 0.225 0.295
Expression system: Cricetulus griseus