PDBe 1b3u

X-ray diffraction
2.3Å resolution

CRYSTAL STRUCTURE OF CONSTANT REGULATORY DOMAIN OF HUMAN PP2A, PR65ALPHA

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Chains: A, B
Molecule details ›
Chains: A, B
Length: 588 amino acids
Theoretical weight: 65.25 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P30153 (Residues: 2-589; Coverage: 100%)
Gene name: PPP2R1A
Sequence domains: HEAT repeat
Structure domains: Leucine-rich Repeat Variant

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX9.6
Spacegroup: P21
Unit cell:
a: 64.28Å b: 112.15Å c: 122.63Å
α: 90° β: 95.6° γ: 90°
R-values:
R R work R free
0.209 0.209 0.268
Expression system: Escherichia coli