PDBe 1azx

X-ray diffraction
2.9Å resolution

ANTITHROMBIN/PENTASACCHARIDE COMPLEX

Released:
Source organism: Homo sapiens
Primary publication:
The anticoagulant activation of antithrombin by heparin.
Proc. Natl. Acad. Sci. U.S.A. 94 14683-8 (1997)
PMID: 9405673

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Antithrombin-III Chains: I, L
Molecule details ›
Chains: I, L
Length: 432 amino acids
Theoretical weight: 49.1 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P01008 (Residues: 33-464; Coverage: 100%)
Gene names: AT3, PRO0309, SERPINC1
Sequence domains: Serpin (serine protease inhibitor)
Structure domains:

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX9.6
Spacegroup: P21
Unit cell:
a: 70.44Å b: 86.97Å c: 97.22Å
α: 90° β: 108.88° γ: 90°
R-values:
R R work R free
0.203 0.195 0.28