PDBe 1alu

X-ray diffraction
1.9Å resolution

HUMAN INTERLEUKIN-6

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Interleukin-6 Chain: A
Molecule details ›
Chain: A
Length: 186 amino acids
Theoretical weight: 21.14 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P05231 (Residues: 28-212; Coverage: 100%)
Gene names: IFNB2, IL6
Structure domains: Growth Hormone; Chain: A;

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH2R
Spacegroup: P3121
Unit cell:
a: 49.678Å b: 49.678Å c: 121.995Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.213 0.213 0.277
Expression system: Escherichia coli