PDBe 1alg

Solution NMR

SOLUTION STRUCTURE OF AN HGR INHIBITOR, NMR, 10 STRUCTURES

Released:

Function and Biology Details

Reaction catalysed:
2 glutathione + NADP(+) = glutathione disulfide + NADPH
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutathione reductase, mitochondrial Chain: A
Molecule details ›
Chain: A
Length: 24 amino acids
Theoretical weight: 2.44 KDa
Source organism: synthetic construct
Expression system: Not provided
UniProt:
  • Canonical: P00390 (Residues: 480-503; Coverage: 5%)
Gene names: GLUR, GRD1, GSR

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Not provided