PDBe 1aie

X-ray diffraction
1.5Å resolution

P53 TETRAMERIZATION DOMAIN CRYSTAL STRUCTURE

Released:
Source organism: Homo sapiens

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cellular tumor antigen p53 Chain: A
Molecule details ›
Chain: A
Length: 31 amino acids
Theoretical weight: 3.77 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P04637 (Residues: 326-356; Coverage: 8%)
Gene names: P53, TP53

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF
Spacegroup: P422
Unit cell:
a: 45.5Å b: 45.5Å c: 33.2Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.191 0.191 0.252
Expression system: Escherichia coli BL21