› 17gs

X-ray diffraction
1.9Å resolution

GLUTATHIONE S-TRANSFERASE P1-1

Released:
DOI: 10.2210/pdb17gs/pdb
PDB entry 17gs coloured by chain, front view.
PDB entry 17gs coloured by chain, side view.
PDB entry 17gs coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Oakley AJ, Lo Bello M, Parker MW

Function and Biology Details

Reaction catalysed: 
RX + glutathione = HX + R-S-glutathione
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140593 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutathione S-transferase P Chains: A, B
Molecule details ›
Chains: A, B
Length: 210 amino acids
Theoretical weight: 23.32 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P09211 (Residues: 1-210; Coverage: 100%)
Gene names: FAEES3, GST3, GSTP1
Sequence domains:
Structure domains:

Ligands and Environments


Cofactor: Ligand GTX 2 x GTX
1 bound ligand:
Ligand MES 3 x MES
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH2R
Spacegroup: C2
Unit cell:
a: 79.213Å b: 90.228Å c: 69.254Å
α: 90° β: 98.61° γ: 90°
R-values:
R R work R free
0.174 0.174 0.2
Expression system: Escherichia coli

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