EMD-9216

Single-particle
3.0 Å
EMD-9216 Deposition: 16/10/2018
Map released: 05/12/2018
Last modified: 18/12/2019
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-9216

Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome

EMD-9216

Single-particle
3.0 Å
EMD-9216 Deposition: 16/10/2018
Map released: 05/12/2018
Last modified: 18/12/2019
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Name: Human 26S proteasome
Complex [1]
Name: Human 26S proteasome
Natural source [1]
Organism: Homo sapiens
Recombinant Expression [1]
Organism Strain Cell Plasmid
Homo sapiens - - -
Complex Portal [2]
Protein [33]
Name: 26S proteasome non-ATPase regulatory subunit 1
Number of copies: 1
UniProtKB UniProtKB PDBe-KB PDBe-KB AlphaFold DB AlphaFold DB
Natural source
Organism: Homo sapiens
Molecular weight
Experimental Theoretical Method
- 105 kDa -
Recombinant Expression
Organism Strain Cell Plasmid
Homo sapiens - - -
Name: 26S proteasome non-ATPase regulatory subunit 3
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Natural source
Organism: Homo sapiens
Molecular weight
Experimental Theoretical Method
- 61 kDa -
Recombinant Expression
Organism Strain Cell Plasmid
Homo sapiens - - -
Name: 26S proteasome non-ATPase regulatory subunit 12
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Natural source
Organism: Homo sapiens
Molecular weight
Experimental Theoretical Method
- 52 kDa -
Recombinant Expression
Organism Strain Cell Plasmid
Homo sapiens - - -
Name: 26S proteasome non-ATPase regulatory subunit 11
Number of copies: 1
UniProtKB UniProtKB PDBe-KB PDBe-KB AlphaFold DB AlphaFold DB
Domains
Natural source
Organism: Homo sapiens
Molecular weight
Experimental Theoretical Method
- 47 kDa -
Recombinant Expression
Organism Strain Cell Plasmid
Homo sapiens - - -
Name: 26S proteasome non-ATPase regulatory subunit 6
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Natural source
Organism: Homo sapiens
Molecular weight
Experimental Theoretical Method
- 45 kDa -
Recombinant Expression
Organism Strain Cell Plasmid
Homo sapiens - - -
Name: 26S proteasome non-ATPase regulatory subunit 7
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Natural source
Organism: Homo sapiens
Molecular weight
Experimental Theoretical Method
- 37 kDa -
Recombinant Expression
Organism Strain Cell Plasmid
Homo sapiens - - -
Name: 26S proteasome non-ATPase regulatory subunit 13
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Natural source
Organism: Homo sapiens
Molecular weight
Experimental Theoretical Method
- 42 kDa -
Recombinant Expression
Organism Strain Cell Plasmid
Homo sapiens - - -
Name: 26S proteasome non-ATPase regulatory subunit 4
Number of copies: 1
UniProtKB UniProtKB PDBe-KB PDBe-KB AlphaFold DB AlphaFold DB
Domains
Natural source
Organism: Homo sapiens
Molecular weight
Experimental Theoretical Method
- 40 kDa -
Recombinant Expression
Organism Strain Cell Plasmid
Homo sapiens - - -
Name: 26S proteasome non-ATPase regulatory subunit 14
EC number: 3.4.19.-
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Natural source
Organism: Homo sapiens
Molecular weight
Experimental Theoretical Method
- 34 kDa -
Recombinant Expression
Organism Strain Cell Plasmid
Homo sapiens - - -
Name: 26S proteasome non-ATPase regulatory subunit 8
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Natural source
Organism: Homo sapiens
Molecular weight
Experimental Theoretical Method
- 39 kDa -
Recombinant Expression
Organism Strain Cell Plasmid
Homo sapiens - - -
Name: 26S proteasome complex subunit SEM1
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Natural source
Organism: Homo sapiens
Molecular weight
Experimental Theoretical Method
- 8 kDa -
Recombinant Expression
Organism Strain Cell Plasmid
Homo sapiens - - -
Name: 26S proteasome non-ATPase regulatory subunit 2
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Natural source
Organism: Homo sapiens
Molecular weight
Experimental Theoretical Method
- 100 kDa -
Recombinant Expression
Organism Strain Cell Plasmid
Homo sapiens - - -
Name: 26S proteasome regulatory subunit 7
Number of copies: 1
UniProtKB PDBe-KB PDBe-KB AlphaFold DB AlphaFold DB
Domains
Natural source
Organism: Homo sapiens
Molecular weight
Experimental Theoretical Method
- 48 kDa -
Recombinant Expression
Organism Strain Cell Plasmid
Homo sapiens - - -
Name: 26S proteasome regulatory subunit 4
Number of copies: 1
UniProtKB UniProtKB PDBe-KB PDBe-KB PDBe-KB AlphaFold DB AlphaFold DB AlphaFold DB
Natural source
Organism: Homo sapiens
Molecular weight
Experimental Theoretical Method
- 49 kDa -
Recombinant Expression
Organism Strain Cell Plasmid
Homo sapiens - - -
Name: 26S proteasome regulatory subunit 8
Number of copies: 1
UniProtKB UniProtKB PDBe-KB PDBe-KB AlphaFold DB AlphaFold DB
Domains
Natural source
Organism: Homo sapiens
Molecular weight
Experimental Theoretical Method
- 44 kDa -
Recombinant Expression
Organism Strain Cell Plasmid
Homo sapiens - - -
Name: 26S proteasome regulatory subunit 6B
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Natural source
Organism: Homo sapiens
Molecular weight
Experimental Theoretical Method
- 47 kDa -
Recombinant Expression
Organism Strain Cell Plasmid
Homo sapiens - - -
Name: 26S proteasome regulatory subunit 10B
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Natural source
Organism: Homo sapiens
Molecular weight
Experimental Theoretical Method
- 45 kDa -
Recombinant Expression
Organism Strain Cell Plasmid
Homo sapiens - - -
Name: 26S proteasome regulatory subunit 6A
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Natural source
Organism: Homo sapiens
Molecular weight
Experimental Theoretical Method
- 49 kDa -
Recombinant Expression
Organism Strain Cell Plasmid
Homo sapiens - - -
Name: Ubiquitin
Number of copies: 2
UniProtKB PDBe-KB AlphaFold DB
Natural source
Organism: Homo sapiens
Molecular weight
Experimental Theoretical Method
- 8 kDa -
Recombinant Expression
Organism Strain Cell Plasmid
Homo sapiens - - -
Name: Proteasome subunit alpha type-6
EC number: 3.4.25.1
Number of copies: 2
UniProtKB PDBe-KB AlphaFold DB
Domains
Natural source
Organism: Homo sapiens
Molecular weight
Experimental Theoretical Method
- 27 kDa -
Recombinant Expression
Organism Strain Cell Plasmid
Homo sapiens - - -
Name: Proteasome subunit alpha type-2
EC number: 3.4.25.1
Number of copies: 2
UniProtKB PDBe-KB AlphaFold DB
Domains
Natural source
Organism: Homo sapiens
Molecular weight
Experimental Theoretical Method
- 25 kDa -
Recombinant Expression
Organism Strain Cell Plasmid
Homo sapiens - - -
Name: Proteasome subunit alpha type-4
EC number: 3.4.25.1
Number of copies: 2
UniProtKB PDBe-KB AlphaFold DB
Domains
Natural source
Organism: Homo sapiens
Molecular weight
Experimental Theoretical Method
- 29 kDa -
Recombinant Expression
Organism Strain Cell Plasmid
Homo sapiens - - -
Name: Proteasome subunit alpha type-7
EC number: 3.4.25.1
Number of copies: 2
UniProtKB PDBe-KB AlphaFold DB
Domains
Natural source
Organism: Homo sapiens
Molecular weight
Experimental Theoretical Method
- 27 kDa -
Recombinant Expression
Organism Strain Cell Plasmid
Homo sapiens - - -
Name: Proteasome subunit alpha type-5
EC number: 3.4.25.1
Number of copies: 2
UniProtKB PDBe-KB AlphaFold DB
Domains
Natural source
Organism: Homo sapiens
Molecular weight
Experimental Theoretical Method
- 26 kDa -
Recombinant Expression
Organism Strain Cell Plasmid
Homo sapiens - - -
Name: Proteasome subunit alpha type-1
EC number: 3.4.25.1
Number of copies: 2
UniProtKB UniProtKB PDBe-KB PDBe-KB AlphaFold DB AlphaFold DB
Domains
Natural source
Organism: Homo sapiens
Molecular weight
Experimental Theoretical Method
- 30 kDa -
Recombinant Expression
Organism Strain Cell Plasmid
Homo sapiens - - -
Name: Proteasome subunit alpha type-3
EC number: 3.4.25.1
Number of copies: 2
UniProtKB PDBe-KB AlphaFold DB
Domains
Natural source
Organism: Homo sapiens
Molecular weight
Experimental Theoretical Method
- 28 kDa -
Recombinant Expression
Organism Strain Cell Plasmid
Homo sapiens - - -
Name: Proteasome subunit beta type-6
EC number: 3.4.25.1
Number of copies: 2
UniProtKB PDBe-KB AlphaFold DB
Domains
Natural source
Organism: Homo sapiens
Molecular weight
Experimental Theoretical Method
- 25 kDa -
Recombinant Expression
Organism Strain Cell Plasmid
Homo sapiens - - -
Name: Proteasome subunit beta type-7
EC number: 3.4.25.1
Number of copies: 2
UniProtKB PDBe-KB AlphaFold DB
Domains
Natural source
Organism: Homo sapiens
Molecular weight
Experimental Theoretical Method
- 29 kDa -
Recombinant Expression
Organism Strain Cell Plasmid
Homo sapiens - - -
Name: Proteasome subunit beta type-3
EC number: 3.4.25.1
Number of copies: 2
UniProtKB PDBe-KB PDBe-KB AlphaFold DB AlphaFold DB
Natural source
Organism: Homo sapiens
Molecular weight
Experimental Theoretical Method
- 22 kDa -
Recombinant Expression
Organism Strain Cell Plasmid
Homo sapiens - - -
Name: Proteasome subunit beta type-2
EC number: 3.4.25.1
Number of copies: 2
UniProtKB PDBe-KB AlphaFold DB
Domains
Natural source
Organism: Homo sapiens
Molecular weight
Experimental Theoretical Method
- 22 kDa -
Recombinant Expression
Organism Strain Cell Plasmid
Homo sapiens - - -
Name: Proteasome subunit beta type-5
EC number: 3.4.25.1
Number of copies: 2
UniProtKB PDBe-KB AlphaFold DB
Domains
Natural source
Organism: Homo sapiens
Molecular weight
Experimental Theoretical Method
- 28 kDa -
Recombinant Expression
Organism Strain Cell Plasmid
Homo sapiens - - -
Name: Proteasome subunit beta type-1
EC number: 3.4.25.1
Number of copies: 2
UniProtKB UniProtKB PDBe-KB PDBe-KB AlphaFold DB AlphaFold DB
Domains
Natural source
Organism: Homo sapiens
Molecular weight
Experimental Theoretical Method
- 26 kDa -
Recombinant Expression
Organism Strain Cell Plasmid
Homo sapiens - - -
Ligand [4]
Name: ZINC ION
HET code: ZN
Number of copies: 1
ChEMBL ChEBI DrugBank
Molecular weight
Experimental Theoretical Method
- 65 Da -
Name: ADENOSINE-5'-TRIPHOSPHATE
HET code: ATP
Number of copies: 4
ChEMBL ChEBI DrugBank
Molecular weight
Experimental Theoretical Method
- 507 Da -
Name: MAGNESIUM ION
HET code: MG
Number of copies: 5
ChEBI DrugBank
Molecular weight
Experimental Theoretical Method
- 24 Da -
Name: ADENOSINE-5'-DIPHOSPHATE
HET code: ADP
Number of copies: 2
ChEMBL ChEBI DrugBank
Molecular weight
Experimental Theoretical Method
- 427 Da -