Helical reconstruction
3.4Å resolution

Cryo-EM structure of NLRC4-CARD filament

Map released:
Last modified:
Overview of EMD-9137
Source organisms:
Fitted atomic model: 6mks
Primary publication:
Cryo-EM structure of the NLRC4CARDfilament provides insights into how symmetric and asymmetric supramolecular structures drive inflammasome assembly.
Matyszewski M, Zheng W, Lueck J, Antiochos B, Egelman EH, Sohn J
J. Biol. Chem. - (2018)
PMID: 30385506

Function and Biology Details

Sample name: NLRC4-CARD filament
Proteins: NLRC4-CARD filament, Chimera protein of NLR family CARD domain-containing protein 4 and EGFP

Experimental Information Details

Resolution: 3.4Å
Resolution method: FSC 0.143 CUT-OFF
Reconstruction software: SPIDER
Microscope: FEI TITAN
Detector: GATAN K2 SUMMIT (4k x 4k)