EMDB EMD-8935

Single particle reconstruction
4.14Å resolution

Ebola virus Makona variant GP (mucin-deleted) in complex with pan-ebolavirus human antibody ADI-15878 Fab

Map released:
Last modified:
Overview of EMD-8935
Source organisms:
Fitted atomic model: 6dzl
Related EM entry by publication: EMD-8936
Primary publication:
Structural Basis of Pan-Ebolavirus Neutralization by an Antibody Targeting the Glycoprotein Fusion Loop.
Murin CD, Bruhn JF, Bornholdt ZA, Copps J, Stanfield R, Ward AB
Cell Rep 24 2723-2732.e4 (2018)
PMID: 30184505

Function and Biology Details

Sample name: Ebola virus Zaire (Makona variant) glycoprotein (mucin-deleted) ectodomain bound to human survivor antibody ADI-15878 Fab
Ligands: N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ALPHA-D-MANNOSE
Proteins: Ebola virus Zaire (Makona variant) glycoprotein (mucin-deleted) ectodomain bound to human survivor antibody ADI-15878 Fab, Ebola virus Zaire (Makona variant) glycoprotein (mucin-deleted) ectodomain, Human survivor antibody ADI-15878 Fab, Ebola virus Makona GP1, Ebola virus Makona GP2, Fv domain of ADI-15878 Fab light chain, Fv domain of ADI-15878 Fab heavy chain

Experimental Information Details

Resolution: 4.14Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C3
Microscope: FEI TALOS ARCTICA
Detector: GATAN K2 SUMMIT (4k x 4k)