EMDB EMD-8782

Single particle reconstruction
3.37Å resolution

Phosphorylated, ATP-bound structure of zebrafish cystic fibrosis transmembrane conductance regulator (CFTR)

Map released:
Last modified:
Overview of EMD-8782
Source organism: Danio rerio [7955]
Fitted atomic model: 5w81
Primary publication:
Conformational Changes of CFTR upon Phosphorylation and ATP Binding.
Zhang Z, Liu F, Chen J
Cell 170 483-491.e8 (2017)
PMID: 28735752

Function and Biology Details

Sample name: zebrafish cystic fibrosis transmembrane conductance regulator (CFTR)
Ligands: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
Proteins: zebrafish cystic fibrosis transmembrane conductance regulator (CFTR), Cystic fibrosis transmembrane conductance regulator

Experimental Information Details

Resolution: 3.37Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C1
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 SUMMIT (4k x 4k)