EMDB EMD-7963

Single particle reconstruction
3.9Å resolution

Cryo-EM structure of human Ptch1

Map released:
Overview of EMD-7963
Source organism: Homo sapiens [9606]
Fitted atomic model: 6dmb
Related EM entry by publication: EMD-7964, EMD-7968
Primary publication:
Structural basis for the recognition of Sonic Hedgehog by human Patched1.
Gong X, Qian H, Cao P, Zhao X, Zhou Q, Lei J, Yan N
Science - (2018)
PMID: 29954986

Function and Biology Details

Sample name: Patch1
Cellular component: Patch1
Ligands: N-ACETYL-D-GLUCOSAMINE, CHOLESTEROL HEMISUCCINATE
Protein: Protein patched homolog 1

Experimental Information Details

Resolution: 3.9Å
Resolution method: FSC 0.143 CUT-OFF
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 SUMMIT (4k x 4k)