EMDB EMD-7869

Single particle reconstruction
3.5Å resolution

Mu Opioid Receptor-Gi Protein Complex

Map released:
Overview of EMD-7869
Source organism: Homo sapiens [9606]
Fitted atomic model: 6ddf
Related EM entry by publication: EMD-7868
Primary publication:
Structure of the mu-opioid receptor-Gi protein complex
Koehl A, Hu H, Maeda S, Zhang Y, Qu Q, Paggi JM, Latorraca NR, Hilger D, Dawson R, Matile H, Schertler GFX, Granier S, Weis WI, Dror RO, Manglik A, Skiniotis G, Kobilka BK
Nature - (2018)

Function and Biology Details

Sample name: Ternary complex of DAMGO-activated Mu-type opioid receptor with heterotrimeric Gi
Proteins: Ternary complex of DAMGO-activated Mu-type opioid receptor with heterotrimeric Gi, Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Mu-type opioid receptor, DAMGO

Experimental Information Details

Resolution: 3.5Å
Resolution method: FSC 0.143 CUT-OFF
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 (4k x 4k)