EMDB EMD-7793

Single particle reconstruction
4.3Å resolution

Thermostablilized dephosphorylated chicken CFTR

Map released:
Last modified:
Overview of EMD-7793
Source organism: Gallus gallus [9031]
Fitted atomic model: 6d3r
Related EM entry by publication: EMD-7794
Primary publication:
Cryo-EM Visualization of an Active High Open Probability CFTR Anion Channel.
Fay JF, Aleksandrov LA, Jensen TJ, Cui LL, Kousouros JN, He L, Aleksandrov AA, Gingerich DS, Riordan JR, Chen JZ
Biochemistry 57 6234-6246 (2018)
PMID: 30281975

Function and Biology Details

Sample name: CFTR
Cellular component: CFTR
Ligand: ADENOSINE-5'-TRIPHOSPHATE
Protein: Cystic fibrosis transmembrane conductance regulator

Experimental Information Details

Resolution: 4.3Å
Resolution method: FSC 1/2 BIT CUT-OFF
Reconstruction software: cryoSPARC
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 SUMMIT (4k x 4k)