EMDB EMD-7461

Single particle reconstruction
7.4Å resolution

Insulin Receptor ectodomain in complex with one insulin molecule

Map released:
Last modified:
Overview of EMD-7461
Source organisms:
Fitted atomic model: 6ce7
Related EM entry by publication: EMD-7462, EMD-7463
Primary publication:
Structure of the insulin receptor-insulin complex by single-particle cryo-EM analysis.
Scapin G, Dandey VP, Zhang Z, Prosise W, Hruza A, Kelly T, Mayhood T, Strickland C, Potter CS, Carragher B
Nature 556 122-125 (2018)
PMID: 29512653

Function and Biology Details

Sample name: Insulin Receptor Ectodomain in complex with one insulin molecule
Proteins: Insulin Receptor Ectodomain in complex with one insulin molecule, Insulin receptor, Insulin A chain, Insulin B chain, Insulin receptor subunit alpha, Insulin receptor, Insulin A chain, Insulin B chain, Insulin receptor subunit alpha

Experimental Information Details

Resolution: 7.4Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C1
Reconstruction software: cryoSPARC
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 QUANTUM (4k x 4k)