EMD-7066

Single-particle
6.5 Å
EMD-7066
3D View Gallery
Deposition: 05/10/2017
Map released: 10/01/2018
Last modified: 09/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-7066
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 6b7z summary report (pdf.gz) Map and 6b7z FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of human insulin degrading enzyme in complex with insulin

EMD-7066

Single-particle
6.5 Å
EMD-7066
3D View Gallery
Deposition: 05/10/2017
Map released: 10/01/2018
Last modified: 09/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Insulin degrading enzyme
Fitted models: 6b7z

Deposition Authors: Zhang Z, Liang WG, Bailey LJ, Tan YZ , Wei H, Kossiakoff AA, Carragher B , Potter SC, Tang WJ
Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Zhang Z, Liang WG, Bailey LJ, Tan YZ , Wei H, Wang A, Farcasanu M, Woods VA, McCord LA, Lee D , Shang W, Deprez-Poulain R , Deprez B, Liu DR, Koide A, Koide S, Kossiakoff AA, Li S, Carragher B , Potter CS , Tang WJ
(2018) eLife , 7
PUBMED: 29596046
DOI: doi:10.7554/eLife.33572
ISSN: 2050-084X