EMDB EMD-7055

Single particle reconstruction
5.2Å resolution

Cryo-EM structure of the NAIP5-NLRC4-flagellin inflammasome

Map released:
Last modified:
Overview of EMD-7055
Source organisms:
Fitted atomic model: 6b5b
Primary publication:
The structural basis of flagellin detection by NAIP5: A strategy to limit pathogen immune evasion.
Tenthorey JL, Haloupek N, Lopez-Blanco JR, Grob P, Adamson E, Hartenian E, Lind NA, Bourgeois NM, Chacon P, Nogales E, Vance RE
Science 358 888-893 (2017)
PMID: 29146805

Function and Biology Details

Sample name: NAIP5-NLRC4-flagellin inflammasome
Proteins: NAIP5-NLRC4-flagellin inflammasome, NAIP5, NLRC4, flagellin, Baculoviral IAP repeat-containing protein 1e, NLR family CARD domain-containing protein 4, Flagellin

Experimental Information Details

Resolution: 5.2Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C1
Reconstruction software: RELION
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 (4k x 4k)