EMD-6997

Single-particle
2.6 Å
EMD-6997
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Deposition: 11/07/2018
Map released: 08/08/2018
Last modified: 06/11/2019
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EMD-6997
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EMICSS annotations (xml)

Complex of voltage-gated sodium channel NavPaS from American cockroach Periplaneta americana bound with tetrodotoxin and Dc1a

EMD-6997

Single-particle
2.6 Å
EMD-6997
3D View Gallery
Deposition: 11/07/2018
Map released: 08/08/2018
Last modified: 06/11/2019
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Name: complex of voltage-gated sodium channel NavPaS from American cockroach Periplaneta americana bound with saxitoxin and Dc1a
Complex [3]
Name: complex of voltage-gated sodium channel NavPaS from American cockroach Periplaneta americana bound with saxitoxin and Dc1a
Molecular weight
Experimental Theoretical Method
- 200 kDa -
Name: voltage-gated sodium channel NavPaS from American cockroach Periplaneta americana
Natural source [1]
Organism: Periplaneta americana
Recombinant Expression [1]
Organism Strain Cell Plasmid
Homo sapiens - - -
Name: Dc1a
Natural source [1]
Organism: Diguetia canities
Recombinant Expression [1]
Organism Strain Cell Plasmid
Escherichia coli - - -
Protein [2]
LEVO
Name: Sodium channel protein PaFPC1
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [6]
Biological process:
regulation of monoatomic ion transmembrane transport regulation of ion transmembrane transport
Molecular function:
voltage-gated monoatomic ion channel activity voltage-gated ion channel activity voltage-gated sodium channel activity
Cellular location:
voltage-gated sodium channel complex
Natural source
Organism: Periplaneta americana
Molecular weight
Experimental Theoretical Method
- 183 kDa -
Recombinant Expression
Organism Strain Cell Plasmid
Homo sapiens - - -
LEVO
Name: Mu-diguetoxin-Dc1a
Number of copies: 1
UniProtKB PDBe-KB AlphaFold DB
Domains
Natural source
Organism: Diguetia canities
Molecular weight
Experimental Theoretical Method
- 6 kDa -
Recombinant Expression
Organism Strain Cell Plasmid
Escherichia coli - - -
Ligand [4]
Name: N-ACETYL-D-GLUCOSAMINE
HET code: NAG
Number of copies: 7
ChEMBL ChEBI
Molecular weight
Experimental Theoretical Method
- 221 Da -
Name: (1R,5R,6R,7R,9S,11S,12S,13S,14S)-3-amino-14-(hydroxymethyl)-8,10-dioxa-2,4-diazatetracyclo[7.3.1.1~7,11~.0~1,6~]tetradec-3-ene-5,9,12,13,14-pentol (non-preferred name)
HET code: 9SR
Number of copies: 1
ChEMBL
Molecular weight
Experimental Theoretical Method
- 319 Da -
Name: SODIUM ION
HET code: NA
Number of copies: 1
ChEBI DrugBank
Molecular weight
Experimental Theoretical Method
- 22 Da -
Name: water
HET code: HOH
Number of copies: 1
ChEMBL ChEBI DrugBank
Molecular weight
Experimental Theoretical Method
- 18 Da -