EMDB EMD-6900

Single particle reconstruction
5.4Å resolution

cASIC+Mambalgin1

Map released:
Last modified:
Overview of EMD-6900
Source organisms:
Related EM entry by publication: EMD-7296
Primary publication:
Cryo-EM structure of the ASIC1a-mambalgin-1 complex reveals that the peptide toxin mambalgin-1 inhibits acid-sensing ion channels through an unusual allosteric effect.
Sun D, Yu Y, Xue X, Pan M, Wen M, Li S, Qu Q, Li X, Zhang L, Li X, Liu L, Yang M, Tian C
Cell Discov 4 27-27 (2018)
PMID: 29872539

Function and Biology Details

Sample name: cASIC and Mambalgin1
Proteins: cASIC and Mambalgin1, cASIC, Mambalgin1, cASIC, Mambalgin1

Experimental Information Details

Resolution: 5.4Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C3
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 QUANTUM (4k x 4k)