EMDB EMD-6826

Single particle reconstruction
5.8Å resolution

structure of endo-lysosomal TRPML1 channel inserting into nanodisc

Map released:
Last modified:
Overview of EMD-6826
Source organism: Mus musculus [10090]
Fitted atomic model: 5ye5
Primary publication:
Cryo-EM structures of the mammalian endo-lysosomal TRPML1 channel elucidate the combined regulation mechanism
Zhang S, Li N, Zeng W, Gao N, Yang M
Protein Cell 8 834-847 (2017)
PMID: 28936784

Function and Biology Details

Sample name: mammalian endo-lysosomal TRPML1 channel
Cellular component: mammalian endo-lysosomal TRPML1 channel
Ligand: N-ACETYL-D-GLUCOSAMINE
Protein: mammalian endo-lysosomal TRPML1 channel

Experimental Information Details

Resolution: 5.8Å
Resolution method: FSC 0.143 CUT-OFF
Reconstruction software: RELION
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 (4k x 4k)