EMDB EMD-6268

Single particle reconstruction
3.92Å resolution

Human TRPA1 ion channel with double antagonist HC030031/A967079

Map released:
Last modified:
Overview of EMD-6268
Source organism: Homo sapiens [9606]
Related EM entry by publication: EMD-6267, EMD-6269
Primary publication:
Structure of the TRPA1 ion channel suggests regulatory mechanisms.
Paulsen CE, Armache JP, Gao Y, Cheng Y, Julius D
NATURE 520 511-517 (2015)
PMID: 25855297

Function and Biology Details

Sample name: Recombinant human TRPA1 treated with HC03031 and A967079
Protein: TRPA1

Experimental Information Details

Resolution: 3.92Å
Resolution method: FSC 0.143, gold-standard
Applied symmetry: C4
Reconstruction software: RELION
Microscope: FEI POLARA 300
Detector: GATAN K2 (4k x 4k)