Single particle reconstruction
29Å resolution

Substrate-specific structural rearrangements of human Dicer

Map released:
Last modified:
Overview of EMD-5602
Source organism: Homo sapiens [9606]
Related EM entries by publication: EMD-5601, EMD-5603, EMD-5604, EMD-5605, EMD-5606
Primary publication:
Substrate-specific structural rearrangements of human Dicer.
Taylor DW, Ma E, Shigematsu H, Cianfrocco MA, Noland CL, Nagayama K, Nogales E, Doudna JA, Wang HW
NAT.STRUCT.MOL.BIOL. 20 662-670 (2013)
PMID: 23624860

Function and Biology Details

Sample name: Human Dicer in complex with a 35 bp pre-siRNA
Nucleic acid: 35 bp pre-siRNA
Protein: Endoribonuclease Dicer

Experimental Information Details

Resolution: 29Å
Resolution method: FSC 0.5
Applied symmetry: C1
Reconstruction software: SPIDER
Microscope: JEOL 3100FFC
Detector: GENERIC GATAN (2k x 2k)