Single particle reconstruction
12.7Å resolution

Electron cryo-microscopy of a cross-beta amyloid fibril polymorph

Map released:
Last modified:
Overview of EMD-5590
Source organism: Rattus norvegicus [10116]
Fitted atomic model: 2m5k
Related EM entry by publication: EMD-2323, EMD-2324
Primary publication:
Atomic structure and hierarchical assembly of a cross-beta amyloid fibril.
Fitzpatrick AW, Debelouchina GT, Bayro MJ, Clare DK, Caporini MA, Bajaj VS, Jaroniec CP, Wang L, Ladizhansky V, Mueller SA, Macphee CE, Waudby CA, Mott HR, De Simone A, Knowles TP, Saibil HR, Vendruscolo M, Orlova EV, Griffin RG, Dobson CM
PROC.NAT.ACAD.SCI.USA 110 5468-5473 (2013)
PMID: 23513222

Function and Biology Details

Sample name: Doublet cross-beta amyloid fibril polymorph
Protein: Transthyretin(105-115)

Experimental Information Details

Resolution: 12.7Å
Resolution method: FSC 0.5
Applied symmetry: C1
Reconstruction software: SPIDER, IMAGIC, BKRP
Microscope: FEI TECNAI F20
Detector: KODAK SO-163 FILM