Helical reconstruction
15Å resolution

3D membrane-bound structure of FVIII bound to single lipid bilayer nanotubes

Map released:
Overview of EMD-5540
Source organism: Homo sapiens [9606]
Related EM entry by publication: EMD-5559
Primary publication:
Domain organization of membrane-bound factor VIII.
Stoilova-McPhie S, Lynch GC, Ludtke S, Pettitt BM
BIOPOLYMERS 99 448-459 (2013)
PMID: 23616213

Function and Biology Details

Sample name: Membrane-bound structure of human Factor VIII light chain helically organized onto single bilayer lipid nanotubes
Protein: blood coagulation Factor VIII light chain

Experimental Information Details

Resolution: 15Å
Resolution method: helical diffraction from Fourier transform
Reconstruction software: EMAN2, IHRSR
Microscope: JEOL 2010F
Detector: GATAN ULTRASCAN 4000 (4k x 4k)