EMDB EMD-3954

Single particle reconstruction
4.8Å resolution

Cryo-EM structure of the human INO80 complex bound to nucleosome

Map released:
Last modified:
Overview of EMD-3954
Source organisms:
Fitted atomic model: 6hts
Primary publication:
Structure and regulation of the human INO80-nucleosome complex.
Ayala R, Willhoft O, Aramayo RJ, Wilkinson M, McCormack EA, Ocloo L, Wigley DB, Zhang X
Nature 556 391-395 (2018)
PMID: 29643506

Function and Biology Details

Sample name: Complex of core human INO80 with nucleosome
Ligands: ADENOSINE-5'-DIPHOSPHATE, ZINC ION
Nucleic acids: DNA (142-MER), DNA (142-MER)
Proteins: Complex of core human INO80 with nucleosome, nucleosome, human INO80, Histone subunits, RuvB-like 1, RuvB-like 2, DNA helicase INO80, Actin-related protein 5, Histone H3.1, Histone H4, Histone H2A type 1-B/E, Histone H2B type 1-J, INO80 complex subunit B

Experimental Information Details

Resolution: 4.8Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C1
Reconstruction software: RELION
Microscope: FEI TITAN KRIOS
Detector: FEI FALCON III (4k x 4k)