EMDB EMD-3754

Single particle reconstruction
3.9Å resolution

The cryo-EM structure of Tick-borne encephalitis virus complexed with Fab fragment of neutralizing antibody 19/1786

Map released:
Overview of EMD-3754
Fitted atomic model: 5o6v
Related EM entry by publication: EMD-3752, EMD-3755
Primary publication:
Structure of tick-borne encephalitis virus and its neutralization by a monoclonal antibody
Fuzik T, Formanova P, Ruzek D, Niedrig M, Plevka P
Nat Commun 9 436- (2018)

Function and Biology Details

Sample name: Tick-borne encephalitis virus (strain HYPR) and Fab
Ligand: N-ACETYL-D-GLUCOSAMINE
Proteins: Mus musculus Fab, Genome polyprotein, Genome polyprotein, Fab 19/1786 - Heavy chain, Fab 19/1786 - Light chain
Viruses: Tick-borne encephalitis virus (strain HYPR) and Fab, Tick-borne encephalitis virus (strain HYPR)

Experimental Information Details

Resolution: 3.9Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: I
Reconstruction software: RELION
Microscope: FEI TITAN KRIOS
Detector: FEI FALCON II (4k x 4k)