EMDB EMD-3749

Single particle reconstruction
4.1Å resolution

Poliovirus type 3 (strain Saukett) stabilized virus-like particle in complex with the pocket factor compound GPP3

Map released:
Last modified:
Overview of EMD-3749
Source organism: Human poliovirus 3 [12086]
Fitted atomic model: 5o5p
Related EM entry by publication: EMD-3747
Primary publication:
Plant-made polio type 3 stabilized VLPs-a candidate synthetic polio vaccine.
Marsian J, Fox H, Bahar MW, Kotecha A, Fry EE, Stuart DI, Macadam AJ, Rowlands DJ, Lomonossoff GP
Nat Commun 8 245-245 (2017)
PMID: 28811473

Function and Biology Details

Sample name: Human poliovirus 3
Ligand: 1-[5-[4-(ethoxyiminomethyl)phenoxy]-3-methyl-pentyl]-3-pyridin-4-yl-imidazol-2-one
Proteins: Capsid proteins, VP1, Capsid proteins, VP2, Capsid proteins, VP3, Genome polyprotein
Virus: Human poliovirus 3

Experimental Information Details

Resolution: 4.1Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: I
Reconstruction software: RELION
Microscope: FEI POLARA 300
Detector: GATAN K2 (4k x 4k)