EMD-2984 Function and Biology

2.2 A resolution cryo-EM structure of beta-galactosidase in complex with a cell-permeant inhibitor

Single particle reconstruction
2.2Å resolution
Overview of EMD-2984
Sample name: Escherichia coli beta-galactosidase bound to phenylethyl beta-D-thiogalactopyranoside (PETG)
Number of unique components: 2
Oligomeric state: tetramer
Theoretical weight (MDa): 0.465
Details: The sample was monodisperse.

beta-galactosidase [Escherichia coli K-12]

Protein type
Name: beta-galactosidase
Alternative name: beta-gal, b-gal
Theoretical weight (MDa): 0.465
Number of copies: 1
Oligomeric state: tetramer
UniProt: P00722
GO: GO:0004565
Natural source of the component
Organism: Escherichia coli K-12
Cellular location: cytoplasm

phenylethyl beta-D-thiogalactopyranoside [unidentified]

Ligand type
Name: phenylethyl beta-D-thiogalactopyranoside
Alternative name: PETG
Number of copies: 4
Oligomeric state: monomer