EMDB EMD-2479

Single particle reconstruction
22Å resolution

Electron microscopy structure of the Drosophila origin recognition complex

Map released:
Overview of EMD-2479
Source organism: Drosophila melanogaster [7227]
Primary publication:
A Meier-Gorlin syndrome mutation in a conserved C-terminal helix of Orc6 impedes origin recognition complex formation.
Bleichert F, Balasov M, Chesnokov I, Nogales E, Botchan MR, Berger JM
ELIFE 2 e00882-e00882 (2013)
PMID: 24137536

Function and Biology Details

Sample name: Drosophila origin recognition complex with ATPgS
Proteins: Orc6, Orc5, Orc4, Orc3, Orc2, Orc1

Experimental Information Details

Resolution: 22Å
Resolution method: FSC 0.5
Applied symmetry: C1
Reconstruction software: SPIDER
Microscope: FEI TECNAI 12
Detector: TVIPS TEMCAM-F416 (4k x 4k)