EMD-2378 Function and Biology

The structure and super-organization of acetylcholine receptor-rapsyn complexes; class B

Subtomogram averaging
41Å resolution
Overview of EMD-2378
Sample name: Postsynaptic membrane isolated from Torpedo marmorata electric organ
Number of unique components: 2
Oligomeric state: acetylcholine receptors bound to a pair of rapsyns
Theoretical weight (MDa): 0.382
Details: class average

nicotinic acetylcholine receptor [Torpedo marmorata]

Protein type
Name: nicotinic acetylcholine receptor
Alternative name: AChR
Experimental weight (MDa): 0.29
Number of copies: 1
InterPro: IPR002394
Natural source of the component
Organism: Torpedo marmorata
Alternative name: Marble electric ray
Organ/Tissue: Electric organ
Cell: Electrocyte
Cellular location: Postsynaptic plasma membrane

Rapsyn [Torpedo marmorata]

Protein type
Name: Rapsyn
Alternative name: 43 kDa receptor-associated protein of the synapse
Experimental weight (MDa): 0.043
Number of copies: 2
GO: GO:0007268, GO:0005515, GO:0008270, GO:0033130, GO:0005856, GO:0030054, GO:0045202, GO:0045211
InterPro: IPR001237, IPR019568, IPR011990, IPR013026, IPR013083, IPR001841, IPR019734, IPR001440, IPR018293
Natural source of the component
Organism: Torpedo marmorata
Alternative name: Marble electric ray
Organ/Tissue: Electric organ
Cell: Electrocyte
Cellular location: Postsynaptic plasma membrane