EMDB EMD-20265

Single particle reconstruction
4.0Å resolution

Cryo-EM structure of voltage-gated sodium channel NavAb N49K/L109A/M116V/G94C/Q150C disulfide crosslinked mutant in the resting state

Map released:
Overview of EMD-20265
Source organism: Arcobacter butzleri (strain RM4018) [367737]
Fitted atomic model: 6p6w
Primary publication:
Resting-State Structure and Gating Mechanism of a Voltage-Gated Sodium Channel.
Wisedchaisri G, Tonggu L, McCord E, Gamal El-Din TM, Wang L, Zheng N, Catterall WA
Cell - (2019)
PMID: 31353218

Function and Biology Details

Sample name: Fusion of maltose-binding protein and voltage-gated sodium channel NavAb in the resting state
Proteins: Fusion of maltose-binding protein and voltage-gated sodium channel NavAb in the resting state, Fusion of Maltose-binding protein and voltage-gated sodium channel NavAb

Experimental Information Details

Resolution: 4.0Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C4
Reconstruction software: cisTEM
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 SUMMIT (4k x 4k)