EMDB EMD-0026

Single particle reconstruction
6.3Å resolution

Neurturin-GFRa2-RET extracellular complex

Map released:
Overview of EMD-0026
Source organism: Homo sapiens [9606]
Fitted atomic model: 6gl7
Primary publication:
Cryo-EM structure of the activated RET signaling complex reveals the importance of its cysteine-rich domain
Bigalke JM, Aibara S, Roth R, Dahl G, Gordon E, Dorbeus S, Amunts A, Sandmark J
Sci Adv - (2019)

Function and Biology Details

Sample name: Neurturin-GFRa2-RET extracellular complex
Proteins: Neurturin-GFRa2-RET extracellular complex, Neurturin, GDNF family receptor alpha-2, Proto-oncogene tyrosine-protein kinase receptor Ret, Neurturin, GDNF family receptor alpha-2, Proto-oncogene tyrosine-protein kinase receptor Ret

Experimental Information Details

Resolution: 6.3Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C2
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 QUANTUM (4k x 4k)