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Showing results 1 to 73 of 73 for InterPro_accession:IPR026591 - New search


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Resolution (Å)
4c78
Complex of human Sirt3 with Bromo-Resveratrol and ACS2 peptide x-ray diffraction 20/11/2013 2.0
4c7b
Complex of human Sirt3 with Bromo-Resveratrol and Fluor-De-Lys peptide x-ray diffraction 20/11/2013 2.1
4ig9
Structure of NAD-dependent protein deacetylase sirtuin-1 (open state, 2.64 A) x-ray diffraction 06/11/2013 2.64
4kxq
Structure of NAD-dependent protein deacetylase sirtuin-1 (closed state, 1.85 A) x-ray diffraction 23/10/2013 1.849
4if6
Structure of NAD-dependent protein deacetylase sirtuin-1 (closed state, 2.25 A) x-ray diffraction 23/10/2013 2.25
4bv3
CRYSTAL STRUCTURE OF SIRT3 IN COMPLEX WITH THE INHIBITOR EX-527 AND NAD x-ray diffraction 17/07/2013 2.0
4bv2
CRYSTAL STRUCTURE OF SIR2 IN COMPLEX WITH THE INHIBITOR EX-527, 2'-O-ACETYL-ADP-RIBOSE AND DEACETYLATED P53-PEPTIDE x-ray diffraction 17/07/2013 3.3
4bvh
CRYSTAL STRUCTURE OF HUMAN SIRT3 IN COMPLEX WITH THE INHIBITOR EX-527 AND 2'-O-ACETYL-ADP-RIBOSE x-ray diffraction 17/07/2013 1.9
4bvb
CRYSTAL STRUCTURE OF HUMAN SIRT3 IN COMPLEX WITH THE INHIBITOR EX-527 AND ADP-RIBOSE x-ray diffraction 17/07/2013 2.0
4bve
CRYSTAL STRUCTURE OF HUMAN SIRT3 IN COMPLEX WITH THIOALKYLIMIDATE FORMED FROM THIO-ACETYL-LYSINE ACS2-PEPTIDE x-ray diffraction 17/07/2013 2.05
4bvf
CRYSTAL STRUCTURE OF HUMAN SIRT3 IN COMPLEX WITH THIOALKYLIMIDATE FORMED FROM THIO-ACETYL-LYSINE ACS2-PEPTIDE CRYSTALLIZED IN PRESENCE OF THE INHIBITOR EX-527 x-ray diffraction 17/07/2013 2.7
4bvg
CRYSTAL STRUCTURE OF HUMAN SIRT3 IN COMPLEX WITH NATIVE ALKYLIMIDATE FORMED FROM ACETYL-LYSINE ACS2-PEPTIDE CRYSTALLIZED IN PRESENCE OF THE INHIBITOR EX-527 x-ray diffraction 17/07/2013 2.5
4buz
SIR2 COMPLEX STRUCTURE MIXTURE OF EX-527 INHIBITOR AND REACTION PRODUCTS OR OF REACTION SUBSTRATES P53 PEPTIDE AND NAD x-ray diffraction 17/07/2013 1.9
4bn4
Structure of human SIRT3 in complex with ADP-ribose x-ray diffraction 26/06/2013 1.3
4bn5
Structure of human SIRT3 in complex with SRT1720 inhibitor x-ray diffraction 26/06/2013 3.25
4jsr
Crystal Structure of human SIRT3 with ELT inhibitor 11c [N-{2-[1-(6-carbamoylthieno[3,2-d]pyrimidin-4-yl)piperidin-4-yl]ethyl}-N'-ethylthiophene-2,5-dicarboxamide] x-ray diffraction 24/04/2013 1.7
4jt8
Crystal Structure of human SIRT3 with ELT inhibitor 28 [4-(4-{2-[(2,2-dimethylpropanoyl)amino]ethyl}piperidin-1-yl)thieno[3,2-d]pyrimidine-6-carboxamide[ x-ray diffraction 24/04/2013 2.26
4jt9
Crystal Structure of human SIRT3 with ELT inhibitor 3 [14-(4-{2-[(methylsulfonyl)amino]ethyl}piperidin-1-yl)thieno[3,2-d]pyrimidine-6-carboxamide] x-ray diffraction 24/04/2013 2.24
4fz3
Crystal structure of SIRT3 in complex with acetyl p53 peptide coupled with 4-amino-7-methylcoumarin x-ray diffraction 20/03/2013 2.1
4i5i
Crystal structure of the SIRT1 catalytic domain bound to NAD and an EX527 analog x-ray diffraction 23/01/2013 2.5
4iao
Crystal structure of Sir2 C543S mutant in complex with SID domain of Sir4 x-ray diffraction 26/12/2012 2.901
4hda
Crystal structure of human Sirt5 in complex with Fluor-de-Lys peptide and resveratrol x-ray diffraction 05/12/2012 2.601
4hd8
Crystal structure of human Sirt3 in complex with Fluor-de-Lys peptide and piceatannol x-ray diffraction 05/12/2012 2.3
4fvt
Human SIRT3 bound to Ac-ACS peptide and Carba-NAD x-ray diffraction 15/08/2012 2.47
4g1c
Human SIRT5 bound to Succ-IDH2 and Carba-NAD x-ray diffraction 15/08/2012 1.944
4f4u
The bicyclic intermediate structure provides insights into the desuccinylation mechanism of SIRT5 x-ray diffraction 20/06/2012 2.0
4f56
The bicyclic intermediate structure provides insights into the desuccinylation mechanism of SIRT5 x-ray diffraction 20/06/2012 1.7
3rig
Sirt5 is an NAD-dependent protein lysine demalonylase and desuccinylase x-ray diffraction 23/11/2011 2.0
3riy
Sirt5 is an NAD-dependent protein lysine demalonylase and desuccinylase x-ray diffraction 23/11/2011 1.55
3u3d
Plasmodium falciparum Sir2A preferentially hydrolyzes medium and long chain fatty acyl lysine x-ray diffraction 09/11/2011 2.4
3u31
Plasmodium falciparum Sir2A preferentially hydrolyzes medium and long chain fatty acyl lysine x-ray diffraction 09/11/2011 2.2
3pdh
Structure of Sir2Tm bound to a propionylated peptide x-ray diffraction 19/01/2011 1.8
3jwp
Crystal structure of Plasmodium falciparum SIR2A (PF13_0152) in complex with AMP x-ray diffraction 20/10/2009 2.65
3jr3
Sir2 bound to acetylated peptide x-ray diffraction 29/09/2009 1.5
3gls
Crystal Structure of Human SIRT3 x-ray diffraction 16/06/2009 2.7
3glr
Crystal Structure of human SIRT3 with acetyl-lysine AceCS2 peptide x-ray diffraction 16/06/2009 1.8
3glu
Crystal Structure of Human SIRT3 with AceCS2 peptide x-ray diffraction 16/06/2009 2.5
3glt
Crystal Structure of Human SIRT3 with ADPR bound to the AceCS2 peptide containing a thioacetyl lysine x-ray diffraction 16/06/2009 2.1
3d81
Sir2-S-alkylamidate complex crystal structure x-ray diffraction 30/09/2008 2.5
3d4b
Crystal structure of Sir2Tm in complex with Acetyl p53 peptide and DADMe-NAD+ x-ray diffraction 30/09/2008 1.9
2hjh
Crystal Structure of the Sir2 deacetylase x-ray diffraction 08/04/2008 1.85
2qqf
Hst2 bound to ADP-HPD and Acetylated histone H4 x-ray diffraction 09/10/2007 2.0
2qqg
Hst2 bound to ADP-HPD, acetyllated histone H4 and nicotinamide x-ray diffraction 09/10/2007 2.05
2od7
Crystal Structure of yHst2 bound to the intermediate analogue ADP-HPD, and and aceylated H4 peptide x-ray diffraction 27/02/2007 2.0
2od9
Structural Basis for Nicotinamide Inhibition and Base Exchange in Sir2 Enzymes x-ray diffraction 27/02/2007 2.05
2od2
Crystal Structure of yHst2 I117F mutant bound to carba-NAD+ and an acetylated H4 peptide x-ray diffraction 20/02/2007 2.0
2nyr
Crystal Structure of Human Sirtuin Homolog 5 in Complex with Suramin x-ray diffraction 19/12/2006 2.06
2h2f
The Structural basis for Sirtuin Substrate affinity x-ray diffraction 05/12/2006 2.2
2h2i
The Structural basis of Sirtuin Substrate Affinity x-ray diffraction 05/12/2006 1.8
2h2h
The Structural basis of sirtuin substrate specificity x-ray diffraction 05/12/2006 2.2
2h2g
The Structural Basis of Sirtuin substrate affinity x-ray diffraction 28/11/2006 1.63
2h2d
The Structural Basis for Sirtuin Substrate Affinity x-ray diffraction 19/09/2006 1.7
2h59
Sir2 H116A-deacetylated p53 peptide-3'-o-acetyl ADP ribose x-ray diffraction 05/09/2006 1.9
2h4j
Sir2-deacetylated peptide (from enzymatic turnover in crystal) x-ray diffraction 05/09/2006 2.1
2h4f
Sir2-p53 peptide-NAD+ x-ray diffraction 05/09/2006 2.0
2h4h
Sir2 H116Y mutant-p53 peptide-NAD x-ray diffraction 05/09/2006 1.99
2b4y
Crystal Structure of Human Sirtuin homolog 5 x-ray diffraction 28/02/2006 1.9
1yc5
Sir2-p53 peptide-nicotinamide x-ray diffraction 26/04/2005 1.4
1yc2
Sir2Af2-NAD-ADPribose-nicotinamide x-ray diffraction 29/03/2005 2.4
1szd
Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD+-dependent Sir2 histone/protein deacetylases x-ray diffraction 15/06/2004 1.5
1szc
Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD+-dependent Sir2 histone/protein deacetylases x-ray diffraction 15/06/2004 1.75
1s5p
Structure and substrate binding properties of cobB, a Sir2 homolog protein deacetylase from Eschericia coli. x-ray diffraction 23/03/2004 1.96
1s7g
Structural Basis for the Mechanism and Regulation of Sir2 Enzymes x-ray diffraction 23/03/2004 2.3
1q1a
Structure of the yeast Hst2 protein deacetylase in ternary complex with 2'-O-acetyl ADP ribose and histone peptide x-ray diffraction 18/11/2003 1.5
1q17
Structure of the yeast Hst2 protein deacetylase in ternary complex with 2'-O-acetyl ADP ribose and histone peptide x-ray diffraction 18/11/2003 2.7
1q14
Structure and autoregulation of the yeast Hst2 homolog of Sir2 x-ray diffraction 30/09/2003 2.5
1m2h
Sir2 homologue S24A mutant-ADP ribose complex x-ray diffraction 08/04/2003 1.8
1m2g
Sir2 homologue-ADP ribose complex x-ray diffraction 08/04/2003 1.7
1m2k
Sir2 homologue F159A mutant-ADP ribose complex x-ray diffraction 08/04/2003 1.47
1m2j
Sir2 homologue H80N mutant-ADP ribose complex x-ray diffraction 08/04/2003 1.7
1m2n
Sir2 homologues (D102G/F159A/R170A) mutant-2'-O-acetyl ADP ribose complex x-ray diffraction 08/04/2003 2.6
1ma3
Structure of a Sir2 enzyme bound to an acetylated p53 peptide x-ray diffraction 16/10/2002 2.0
1ici
CRYSTAL STRUCTURE OF A SIR2 HOMOLOG-NAD COMPLEX x-ray diffraction 02/05/2001 2.1
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