› 9ins

X-ray diffraction
1.7Å resolution

MONOVALENT CATION BINDING IN CUBIC INSULIN CRYSTALS

Released:
DOI: 10.2210/pdb9ins/pdb
PDB entry 9ins coloured by chain, front view.
PDB entry 9ins coloured by chain, side view.
PDB entry 9ins coloured by chain, top view.
Source organism: Sus scrofa
Primary publication:
Monovalent cation binding to cubic insulin crystals.
Gursky O, Li Y, Badger J, Caspar DL
Biophys J 61 604-11 (1992)
PMID: 1504238

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
hetero dimer (preferred)
hetero tetramer
Assembly name:
PDBe Complex ID:
PDB-CPX-134237 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Insulin A chain Chain: A
Molecule details ›
Chain: A
Length: 21 amino acids
Theoretical weight: 2.38 KDa
Source organism: Sus scrofa
Expression system: Not provided
UniProt:
  • Canonical: P01315 (Residues: 88-108; Coverage: 25%)
Gene name: INS
Insulin B chain Chain: B
Molecule details ›
Chain: B
Length: 30 amino acids
Theoretical weight: 3.4 KDa
Source organism: Sus scrofa
Expression system: Not provided
UniProt:
  • Canonical: P01315 (Residues: 25-54; Coverage: 36%)
Gene name: INS
Sequence domains: Insulin/IGF/Relaxin family

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: I213
Unit cell:
a: 78.9Å b: 78.9Å c: 78.9Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.178 not available not available
Expression system: Not provided

Quick links

Citations

16 citation in other articles

Protein-protein interaction at crystal contacts.
Janin et al. (1995)
15 more

16 mentions without citation

Breaking symmetry in protein dimers: designs and functions.
Brown JH. (2006)
15 more