7nn9 Summary


PDB entry 7nn9 (supersedes 2nn9)


The structure was published by Varghese, J.N., Epa, V.C., and Colman, P.M., in 1995 in a paper entitled "Three-dimensional structure of the complex of 4-guanidino-Neu5Ac2en and influenza virus neuraminidase." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.0 Å and deposited in 1995.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of NEURAMINIDASE N9. This molecule has the UniProt identifier P03472 (NRAM_I75A5)search. The sample contained 388 residues which is < 90% of the natural sequence. Out of 388 residues 388 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms homotetramers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A NEURAMINIDASE N9 P03472 (83-470) (NRAM_I75A5)search Influenza A virus (A/tern/Australia/G70C/1975(H11N9))search < 90% 388 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P03472 (83 - 470) NEURAMINIDASE N9 Influenza A virus (A/tern/Australia/G70C/1975(H11N9))

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A Sialidases (neuraminidases)search Neuraminidasesearch Neuraminidasesearch

Chain ID Cellular component (GO) Biological process (GO) Molecular function (GO)
A (P03472) membranesearch host cell membranesearch virion membranesearch carbohydrate metabolic processsearch exo-alpha-sialidase activitysearch

Chain InterPro annotation
A Glycoside hydrolase, family 34search Sialidasessearch