› 6vkj

X-ray diffraction
2.1Å resolution

Crystal structure of the G domain of human guanylate-binding protein 2 (hGBP2) in complex with GDP

Released:
DOI: 10.2210/pdb6vkj/pdb
PDB entry 6vkj coloured by chain, front view.
PDB entry 6vkj coloured by chain, side view.
PDB entry 6vkj coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Roy S, Wang B, Tian Y, Yin Q

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152322 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Guanylate-binding protein 2 Chain: A
Molecule details ›
Chain: A
Length: 305 amino acids
Theoretical weight: 34.01 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P32456 (Residues: 5-309; Coverage: 52%)
Gene name: GBP2
Sequence domains: Guanylate-binding protein, N-terminal domain

Ligands and Environments

1 bound ligand:
Ligand GDP 1 x GDP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS-II BEAMLINE 17-ID-1
Spacegroup: P41212
Unit cell:
a: 87.951Å b: 87.951Å c: 105.279Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.184 0.181 0.226
Expression system: Escherichia coli BL21(DE3)

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