› 6pti

X-ray diffraction
1.7Å resolution

STRUCTURE OF FORM III CRYSTALS OF BOVINE PANCREATIC TRYPSIN INHIBITOR

Released:
DOI: 10.2210/pdb6pti/pdb
PDB entry 6pti coloured by chain, front view.
PDB entry 6pti coloured by chain, side view.
PDB entry 6pti coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
Structure of form III crystals of bovine pancreatic trypsin inhibitor.
Wlodawer A, Nachman J, Gilliland GL, Gallagher W, Woodward C
J Mol Biol 198 469-80 (1987)
PMID: 2448484

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-133749 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Pancreatic trypsin inhibitor Chain: A
Molecule details ›
Chain: A
Length: 58 amino acids
Theoretical weight: 6.53 KDa
Source organism: Bos taurus
Expression system: Not provided
UniProt:
  • Canonical: P00974 (Residues: 36-93; Coverage: 73%)
Sequence domains: Kunitz/Bovine pancreatic trypsin inhibitor domain
Structure domains: Pancreatic trypsin inhibitor Kunitz domain

Ligands and Environments

1 bound ligand:
Ligand PO4 1 x PO4
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P21212
Unit cell:
a: 55.2Å b: 38.2Å c: 24.05Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.16 not available not available
Expression system: Not provided

Quick links

Citations

10 review citations

Natural protein proteinase inhibitors and their interaction with proteinases.
Bode et al. (1992)
9 more

29 mentions without citation

Protonation and pK changes in protein-ligand binding.
Onufriev et al. (2013)
28 more