Function and Biology Details
Reaction catalysed:
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-120325 (preferred)
Entry contents:
2 distinct polypeptide molecules
2 distinct DNA molecules
2 distinct DNA molecules
Macromolecules (4 distinct):
DNA-directed DNA polymerase
Molecule details ›
Chain: H
Length: 704 amino acids
Theoretical weight: 79.81 KDa
Source organism: Escherichia phage T7
Expression system: Escherichia coli
UniProt:
Sequence domains: DNA polymerase family A
Length: 704 amino acids
Theoretical weight: 79.81 KDa
Source organism: Escherichia phage T7
Expression system: Escherichia coli
UniProt:
- Canonical:
P00581 (Residues: 1-704; Coverage: 100%)
Sequence domains: DNA polymerase family A
Thioredoxin 1
Molecule details ›
Chain: I
Length: 109 amino acids
Theoretical weight: 11.82 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
Sequence domains: Thioredoxin
Length: 109 amino acids
Theoretical weight: 11.82 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
- Canonical: P0AA25 (Residues: 1-109; Coverage: 100%)
Sequence domains: Thioredoxin
