Function and Biology Details
Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Phosphatidylinositol 3-/4-kinase, catalytic domain
- Nonsense-mediated mRNA decay factor SMG8-like
- FATC domain
- Armadillo-type fold
- P-loop containing nucleoside triphosphate hydrolase
- Nonsense-mediated mRNA decay factor SMG9
- Nonsense-mediated mRNA decay factor SMG8
- Phosphatidylinositol 3/4-kinase, conserved site
7 more domains
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
SMG1C protein kinase complex (preferred)
PDBe Complex ID:
PDB-CPX-185493 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Serine/threonine-protein kinase SMG1
Molecule details ›
Nonsense-mediated mRNA decay factor SMG8
Nonsense-mediated mRNA decay factor SMG9
Molecule details ›
Chain: C
Length: 520 amino acids
Theoretical weight: 57.72 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Length: 520 amino acids
Theoretical weight: 57.72 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical:
Q9H0W8 (Residues: 1-520; Coverage: 100%)
