› 6kx0

X-ray diffraction
2.4Å resolution

Crystal structure of SN-101 mAb non-liganded form

Released:
DOI: 10.2210/pdb6kx0/pdb
PDB entry 6kx0 coloured by chain, front view.
PDB entry 6kx0 coloured by chain, side view.
PDB entry 6kx0 coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
A straightforward approach to antibodies recognising cancer specific glycopeptidic neoepitopes
Wakui H, Tanaka Y, Ose T, Matsumoto I, Kato K, Min Y, Tachibana T, Sato M, Naruchi K, Martin FG, Hinou H, Nishimura S-I
Chem Sci 11 4999-5006 (2020)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-214100 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Fab Fragment-SN-101-Heavy chain Chain: A
Molecule details ›
Chain: A
Length: 236 amino acids
Theoretical weight: 25.54 KDa
Source organism: Mus musculus
Expression system: Mus musculus
Fab Fragment-SN-101-Light chain Chain: B
Molecule details ›
Chain: B
Length: 239 amino acids
Theoretical weight: 26.44 KDa
Source organism: Mus musculus
Expression system: Mus musculus

Ligands and Environments

1 bound ligand:
Ligand TRS 2 x TRS
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-17A
Spacegroup: C2
Unit cell:
a: 159.86Å b: 40.1Å c: 67.78Å
α: 90° β: 99.83° γ: 90°
R-values:
R R work R free
0.228 0.225 0.278
Expression system: Mus musculus

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