› 6jjf

X-ray diffraction
1.47Å resolution

Crystal structure of a two-quartet DNA mixed-parallel/antiparallel G-quadruplex

Released:
DOI: 10.2210/pdb6jjf/pdb
PDB entry 6jjf coloured by chain, front view.
PDB entry 6jjf coloured by chain, side view.
PDB entry 6jjf coloured by chain, top view.
Source organism: Pseudorabies virus Ea
Primary publication:
Native de novo structural determinations of non-canonical nucleic acid motifs by X-ray crystallography at long wavelengths.
Zhang Y, El Omari K, Duman R, Liu S, Haider S, Wagner A, Parkinson GN, Wei D
Nucleic Acids Res 48 9886-9898 (2020)
PMID: 32453431

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-120078 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
DNA (5'-D(*GP*GP*CP*TP*CP*GP*GP*CP*GP*GP*CP*GP*GP*A)-3') Chains: A, B
Molecule details ›
Chains: A, B
Length: 14 nucleotides
Theoretical weight: 4.36 KDa
Source organism: Pseudorabies virus Ea
Expression system: Not provided

Ligands and Environments

3 bound ligands:
Ligand K 3 x K
Ligand NCO 3 x NCO
Ligand NA 1 x NA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I23
Spacegroup: C2
Unit cell:
a: 45.37Å b: 47.6Å c: 37.73Å
α: 90° β: 110.02° γ: 90°
R-values:
R R work R free
0.192 0.192 0.199
Expression system: Not provided

Quick links

Citations

3 review citations

Pseudorabies Virus: From Pathogenesis to Prevention Strategies.
Zheng et al. (2022)
2 more

1 mention without citation

Native de novo structural determinations of non-canonical nucleic acid motifs by X-ray crystallography at long wavelengths.
Zhang et al. (2020)