› 6di7

X-ray diffraction
2.3Å resolution

Vps1 GTPase-BSE fusion complexed with GDP

Released:
DOI: 10.2210/pdb6di7/pdb
PDB entry 6di7 coloured by chain, front view.
PDB entry 6di7 coloured by chain, side view.
PDB entry 6di7 coloured by chain, top view.
Source organism: Chaetomium thermophilum var. thermophilum DSM 1495
Primary publication:
Structures of the fungal dynamin-related protein Vps1 reveal a unique, open helical architecture.
Varlakhanova NV, Alvarez FJD, Brady TM, Tornabene BA, Hosford CJ, Chappie JS, Zhang P, Ford MGJ
J Cell Biol 217 3608-3624 (2018)
PMID: 30087125

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-124101 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Putative sorting protein Chain: A
Molecule details ›
Chain: A
Length: 386 amino acids
Theoretical weight: 42.38 KDa
Source organism: Chaetomium thermophilum var. thermophilum DSM 1495
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: G0SFF0 (Residues: 1-358; Coverage: 51%)
Gene name: CTHT_0061810
Sequence domains:

Ligands and Environments

2 bound ligands:
Ligand GDP 1 x GDP
Ligand MG 1 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: R32
Unit cell:
a: 84.979Å b: 84.979Å c: 271.502Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.178 0.177 0.199
Expression system: Escherichia coli BL21

Quick links

Citations

2 review citations

The structural biology of the dynamin-related proteins: New insights into a diverse, multitalented family.
Ford et al. (2019)
1 more

2 mentions without citation

Structures of the fungal dynamin-related protein Vps1 reveal a unique, open helical architecture.
Varlakhanova et al. (2018)
1 more