Function and Biology Details
Reaction catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- RNA polymerase sigma-70
- DNA-directed RNA polymerase, insert domain superfamily
- DNA-directed RNA polymerase, RpoA/D/Rpb3-type
- RNA polymerase, RBP11-like subunit
- DNA-directed RNA polymerase, alpha subunit
- DNA-directed RNA polymerase, omega subunit
- RNA polymerase-binding protein RbpA
- Winged helix-like DNA-binding domain superfamily
38 more domains
Structure analysis Details
Assembly composition:
hetero nonamer (preferred)
PDBe Complex ID:
PDB-CPX-106287 (preferred)
Entry contents:
7 distinct polypeptide molecules
1 distinct DNA molecule
1 distinct DNA molecule
Macromolecules (8 distinct):
RNA polymerase-binding protein RbpA
Molecule details ›
Chain: J
Length: 114 amino acids
Theoretical weight: 13.08 KDa
Source organism: Mycolicibacterium smegmatis MC2 155
Expression system: Escherichia coli
UniProt:
Sequence domains: RNA polymerase-binding protein
Length: 114 amino acids
Theoretical weight: 13.08 KDa
Source organism: Mycolicibacterium smegmatis MC2 155
Expression system: Escherichia coli
UniProt:
- Canonical:
A0QZ11 (Residues: 1-114; Coverage: 100%)
Sequence domains: RNA polymerase-binding protein
DNA-directed RNA polymerase subunit alpha
Molecule details ›
Chains: A, B
Length: 350 amino acids
Theoretical weight: 37.96 KDa
Source organism: Mycolicibacterium smegmatis MC2 155
UniProt:
Sequence domains:
Length: 350 amino acids
Theoretical weight: 37.96 KDa
Source organism: Mycolicibacterium smegmatis MC2 155
UniProt:
- Canonical: A0QSL8 (Residues: 1-350; Coverage: 100%)
Sequence domains:
- RNA polymerase Rpb3/Rpb11 dimerisation domain
- RNA polymerase Rpb3/RpoA insert domain
- Bacterial RNA polymerase, alpha chain C terminal domain
DNA-directed RNA polymerase subunit beta
Molecule details ›
Chain: C
Length: 1169 amino acids
Theoretical weight: 128.68 KDa
Source organism: Mycolicibacterium smegmatis MC2 155
UniProt:
Sequence domains:
Length: 1169 amino acids
Theoretical weight: 128.68 KDa
Source organism: Mycolicibacterium smegmatis MC2 155
UniProt:
- Canonical: P60281 (Residues: 1-1169; Coverage: 100%)
Sequence domains:
DNA-directed RNA polymerase subunit beta'
Molecule details ›
Chain: D
Length: 1317 amino acids
Theoretical weight: 146.71 KDa
Source organism: Mycolicibacterium smegmatis MC2 155
UniProt:
Sequence domains:
Length: 1317 amino acids
Theoretical weight: 146.71 KDa
Source organism: Mycolicibacterium smegmatis MC2 155
UniProt:
- Canonical: A0QS66 (Residues: 1-1317; Coverage: 100%)
Sequence domains:
DNA-directed RNA polymerase subunit omega
Molecule details ›
Chain: E
Length: 107 amino acids
Theoretical weight: 11.54 KDa
Source organism: Mycolicibacterium smegmatis MC2 155
UniProt:
Sequence domains: RNA polymerase Rpb6
Length: 107 amino acids
Theoretical weight: 11.54 KDa
Source organism: Mycolicibacterium smegmatis MC2 155
UniProt:
- Canonical: A0QWT1 (Residues: 1-107; Coverage: 100%)
Sequence domains: RNA polymerase Rpb6
RNA polymerase sigma factor SigA
Molecule details ›
Chain: F
Length: 466 amino acids
Theoretical weight: 51.57 KDa
Source organism: Mycolicibacterium smegmatis MC2 155
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 466 amino acids
Theoretical weight: 51.57 KDa
Source organism: Mycolicibacterium smegmatis MC2 155
Expression system: Escherichia coli
UniProt:
- Canonical: A0QW02 (Residues: 1-466; Coverage: 100%)
Sequence domains:
