› 6rhn

X-ray diffraction
2.15Å resolution

HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN (HINT) FROM RABBIT WITHOUT NUCLEOTIDE

Released:
DOI: 10.2210/pdb6rhn/pdb
PDB entry 6rhn coloured by chain, front view.
PDB entry 6rhn coloured by chain, side view.
PDB entry 6rhn coloured by chain, top view.
Source organism: Oryctolagus cuniculus
Primary publication:
Crystal structures of HINT demonstrate that histidine triad proteins are GalT-related nucleotide-binding proteins.
Brenner C, Garrison P, Gilmour J, Peisach D, Ringe D, Petsko GA, Lowenstein JM
Nat Struct Biol 4 231-8 (1997)
PMID: 9164465

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160462 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Adenosine 5'-monophosphoramidase HINT1 Chain: A
Molecule details ›
Chain: A
Length: 115 amino acids
Theoretical weight: 12.58 KDa
Source organism: Oryctolagus cuniculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P80912 (Residues: 12-126; Coverage: 91%)
Gene names: HINT, HINT1
Sequence domains: HIT domain
Structure domains: HIT-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH2R
Spacegroup: P43212
Unit cell:
a: 40.34Å b: 40.34Å c: 143.03Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.176 0.176 0.263
Expression system: Escherichia coli

Quick links

Citations

16 review citations

Diadenosine oligophosphates (Ap(n)A), a novel class of signalling molecules?
Kisselev et al. (1998)
15 more

5 mentions without citation

Enzyme nanorings.
Chou et al. (2008)
4 more